The tractor-trailer carrying building supplies was in a single vehicle rollover-- while on the ramp-- around 6:30 a.m., according to police.
A tow-truck arrived at the scene around 7:30 a.m., according to dispatch.
All Route 30 East traffic intending to go north on Route 222 was diverted to the next interchange at New Holland Pike, say police.
The ramp was closed for nearly three hours, while emergency crews cleaned up the scene, according to dispatch.
Traffic delays continued in the area around 10 a.m., and police continue to ask drivers to consider alternative routes.
Click here to follow Daily Voice Cornwall-Mount Gretna and receive free news updates.